1204246-72-9Relevant articles and documents
Synthesis of 1- and 5-(pyrazolyl)tetrazole amino and nitro derivatives
Dalinger, Igor L.,Kormanov, Alexandr V.,Vatsadze, Irina A.,Serushkina, Olga V.,Shkineva, Tatyana K.,Suponitsky, Kyrill Yu.,Pivkina, Alla N.,Sheremetev, Aleksei B.
, p. 1025 - 1034 (2016)
Regioselective introduction of nitro groups was studied in the case of pyrazoles containing a 1- or 5-tetrazole substituent at position 3(5). All the possible isomeric C-mononitropyrazoles were synthesized. The reduction of these compounds gave the respective 3(5)-amino-5(3)-tetrazolylpyrazoles, which were nitrated to 3(5)-nitramino-4-nitro-5(3)-tetrazolylpyrazoles. The reaction of 1-(nitropyrazol- 3(5)-yl)tetrazoles with hydroxylamine-O-sulfonic acid produced the respective N-amino derivatives.
ADENOSINE A3 RECEPTOR MODULATING COMPOUNDS AND METHODS OF USE THEREOF
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, (2012/03/12)
Provided herein is a method of preventing, treating, or ameliorating one or more symptoms of an adenosine A3-mediated condition, disorder, or disease, with a compound of Formula I. Also provided herein is a method of preventing, treating, or ameliorating one or more symptoms of glaucoma or ocular hypertension. Further provided herein is a method of modulating the activity of an adenosine A3 receptor.
JAK KINASE MODULATING QUINAZOLINE DERIVATIVES AND METHODS OF USE THEREOF
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Page/Page column 95, (2010/09/17)
Provided herein are quinazoline compounds for treatment of JAK kinase mediated diseases, including JAK2 kinase-, JAK3 kinase- or TYK2 kinase-mediated diseases. Also provided are pharmaceutical compositions comprising the compounds and methods of using the compounds and compositions. (I).
