1204306-92-2

Upstream product

• 119-65-3 isoquinoline 
• 1034004-80-2 [(1,1'-ferrocenylene(NSitBuMe₂)2)Y(tetrahydrofuran)(benzyl)] 

Downstream Products

• 1204306-79-5 [(1,1'-ferrocenylene(NSi(tBu)Me2)2)Y(1-benzylisoquinoline)(η2-PhNNHPh)]*toluene 
• 1204306-77-3 [(1,1'-ferrocenylene(NSitBuMe₂)2)Y(tetrahydrofuran)(1-benzylisoquinoline(-H))] 
• 1204306-83-1 [(1,1'-ferrocenylene(NSi(tBu)Me₂)2)Y(tetrahydrofuran)2(C₉H₈N)] 
• 1204306-96-6 [(1,1'-ferrocenylene(NSi(tBu)Me₂)2)Y(isoquinoline)2(OCHPh₂)] 

Relevant academic research and scientific papers

Dearomatization reactions of N-heterocycles mediated by group 3 complexes

Group 3 (Sc, Y, Lu, La) benzyl complexes supported by a ferrocene diamide ligand are reactive toward aromatic N-heterocycles by mediating their coupling and, in a few cases, the cleavage of their C-N bonds. When these complexes reacted with 2,2′-bipyridine or isoquinoline, they facilitated the alkyl migration of the benzyl ligand onto the pyridine ring, a process accompanied by the dearomatization of the N-heterocycle. The products of the alkyl-transfer reactions act as hydrogen donors in the presence of aromatic N-heterocycles, ketones, and azobenzene. Experimental and computational studies suggest that the hydrogen transfer takes place through a concerted mechanism. An interesting disproportionation reaction of the dearomatized, alkyl-substituted isoquinoline complexes is also reported.