1204390-45-3 Usage
Description
6-chloroquinazoline-2-carboxylic acid is a quinazoline derivative with the molecular formula C9H5ClN2O2, featuring a chloro substituent at the 6-position and a carboxylic acid group at the 2-position. This chemical compound serves as a building block in the pharmaceutical industry for synthesizing various bioactive compounds and pharmaceuticals.
Uses
Used in Pharmaceutical Industry:
6-chloroquinazoline-2-carboxylic acid is used as a building block for the synthesis of various bioactive compounds and pharmaceuticals, contributing to the development of new drugs and therapeutic agents.
Used in Antitumor Applications:
In the field of oncology, 6-chloroquinazoline-2-carboxylic acid is used as a potential antitumor agent, being studied for its therapeutic applications in treating cancer.
Used in Anti-inflammatory Applications:
6-chloroquinazoline-2-carboxylic acid is also used as a potential anti-inflammatory agent, indicating its possible use in managing inflammation-related conditions.
Used as a Research Tool:
Furthermore, 6-chloroquinazoline-2-carboxylic acid may be utilized as a research tool in the development of new drugs and therapeutic agents, aiding in scientific investigations and pharmacological studies.
Check Digit Verification of cas no
The CAS Registry Mumber 1204390-45-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,3,9 and 0 respectively; the second part has 2 digits, 4 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1204390-45:
(9*1)+(8*2)+(7*0)+(6*4)+(5*3)+(4*9)+(3*0)+(2*4)+(1*5)=113
113 % 10 = 3
So 1204390-45-3 is a valid CAS Registry Number.
1204390-45-3Relevant articles and documents
Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: Exploration of 6-6 fused rings as alternative S1 moieties
Yoshikawa, Kenji,Kobayashi, Shozo,Nakamoto, Yumi,Haginoya, Noriyasu,Komoriya, Satoshi,Yoshino, Toshiharu,Nagata, Tsutomu,Mochizuki, Akiyoshi,Watanabe, Kengo,Suzuki, Makoto,Kanno, Hideyuki,Ohta, Toshiharu
, p. 8221 - 8233 (2009)
A series of cis-1,2-diaminocyclohexane derivatives possessing a 6-6 fused ring for the S1 moiety were synthesized as novel factor Xa (fXa) inhibitors. The synthesis, structure-activity relationship (SAR), and physicochemical properties are reported herein, together with the discovery of compound 45c, which has potent anti-fXa activity, good physicochemical properties and pharmacokinetic (PK) profiles, including a reduced negative food effect.
