1204391-07-0

Basic information

• Product Name: C₂₆H₃₄N₂O₄
• Synonyms: C₂₆H₃₄N₂O₄
• CAS NO: 1204391-07-0
• Molecular Weight: 438.567
• Mol File: 1204391-07-0.mol

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₄N₂O₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₄N₂O₄(1204391-07-0)
• EPA Substance Registry System: C₂₆H₃₄N₂O₄(1204391-07-0)

Safety Data

• Hazardous Substances Data: 1204391-07-0(Hazardous Substances Data)

Upstream product

• 150884-50-7 benzaldehyde N-boc imine 

Relevant articles and documents

N-Boc-aminals as easily accessible precursors for less accessible N-Boc-imines: Facile synthesis of optically active propargylamine derivatives using Mannich-type reactions

We developed a facile and practical synthesis of N-Boc-aminals, which can be used as precursors for less accessible N-Boc-imines. Aminals were obtained via simple dehydration condensation reactions of t-butyl carbamate (BocNH2) and various aldehydes in acetic anhydride, followed by filtration and washing with hexane. The obtained N-Boc-alkynylaminals could be successfully applied in enantioselective Mannich-type reactions, catalyzed by chiral phosphoric acids, to afford optically active propargylamine derivatives.

Br?nsted acid-catalyzed Mannich reaction through dual activation of aldehydes and N-Boc-imines

In the presence of a Br?nsted acid catalyst, both aldehydes and N-Boc-aminals were converted to enecarbamates and N-Boc-iminium salts as activated nucleophiles and electrophiles, respectively, giving unprecedented Mannich adducts. The asymmetric variant of the present Mannich reaction has also been demonstrated with a chiral phosphoric acid catalyst.

Trimethylchlorosilane-promoted aza-Mannich reaction of enecarbamates and aldimines

A trimethylchlorosilane-promoted aza-Mannich reaction is reported utilizing enecarbamates as the nucleophile and aromatic N-Boc aldimines as the electrophile. A variety of nucleophiles and electrophiles are tolerated by the reaction conditions, delivering