1204397-10-3Relevant academic research and scientific papers
Chiral amine-induced stereoselectivity in trans-β-lactam formation via Staudinger cycloaddition
Todorov, Aleksandar R.,Kurteva, Vanya B.,Bontchev, Ranko P.,Vassilev, Nikolay G.
experimental part, p. 10339 - 10347 (2010/02/27)
A series of chiral trans-β-lactams was obtained via Staudinger cycloaddition with low to moderate diastereoselectivity (up to 54% de) induced by a chiral amine component of the imine. It was shown that the direct connection of nitrogen to a chiral centre
