120445-32-1

Basic information

• Product Name: CBZ-Alanyl-(S)-phenyllactic acid methyl ester
• CAS NO: 120445-32-1
• Molecular Weight: 385.417
• Mol File: 120445-32-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: CBZ-Alanyl-(S)-phenyllactic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: CBZ-Alanyl-(S)-phenyllactic acid methyl ester(120445-32-1)
• EPA Substance Registry System: CBZ-Alanyl-(S)-phenyllactic acid methyl ester(120445-32-1)

Safety Data

• Hazardous Substances Data: 120445-32-1(Hazardous Substances Data)

Upstream product

• 1142-20-7 N-Cbz-Ala 
• 13673-95-5 (S)-methyl 2-hydroxy-3-phenylpropanoate 

Relevant articles and documents

1,1'-Carbonylbis(3-methylimidazolium) Triflate: An Efficient Reagent for Aminoacylations

Amino acid carboxyl activation and subsequent coupling with nucleophiles frequently suffer from uncertain risks of racemization, complex reagent preparation, or troublesome side-product removal.All of these difficulties are eliminated with a new, simple reagent, 1,1'-carbonylbis(3-methylimidazolium) triflate (CBMIT), obtainable readily by bis-alkylation of carbonyldiimidazole with methyl triflate.Via a highly reactive acyl imidazolium intermediate, CBMIT couples amino acid components or amino acids and alcohols to give peptides and esters, easily isolated in high yield.The reaction medium remains free of any base, and no loss of optical activity is observed.