1204473-87-9Relevant academic research and scientific papers
Rhodium-catalyzed functionalization of sterically hindered alkenes
Gendrineau, Thomas,Genet, Jean-Pierre,Darses, Sylvain
supporting information; experimental part, p. 308 - 310 (2010/03/24)
(Figure presented) For the first time the rhodium-catalyzed 1,4-addition of organoboranes to hindered Baylis-Hillman adducts, trisubstituted alkenes, affording highly functionalized alkenes, via addition of the organoboranes and hydroxyelimination, Is reported. Moreover, preliminary results have shown that, thanks to the use of a monosubstituted chiral diene ligand, enantio-enriched products were easily accessible, while chiral phosphane ligands were completely inappropriate in this reaction.
