120450-40-0Relevant academic research and scientific papers
Pyridine and nitro-phenyl linked 1,3,4-thiadiazoles as MDR-TB inhibitors
Patel, Harun,Jadhav, Harsha,Ansari, Iqrar,Pawara, Rahul,Surana, Sanjay
, p. 1 - 9 (2019/02/14)
In the present study, a series of substituted 1,3,4-thiadiazole derivatives 4(a–o), 5(a–m) and 6(a–j) were synthesized and characterized by IR, 1H NMR, 13C NMR and mass spectroscopic technique. The synthesized compounds were evaluate
Synthesis of 6-Aroylimino-2-aryl-1,3,4-thiadiazolothiadiazolines
Sridevi, G.,Rao, P. Jayaprasad,Reddy, K. Kondal
, p. 997 - 1000 (2007/10/02)
Reaction of 2-amino-5-aryl-1,3,4-thiadiazoles (V) with aroyl isothiocyanates gives 2-aroylamino-5-aryl-1,3,4-thiadiazoles (VII) and N-aroyl-N'-(5-aryl-1,3,4-thiadiazol-2-yl)thioureas (VIII).Contrary to earlier reports, cyclisation of VIII in the presence of PCl5 in POCl3 yields 6-aroylimino-2-aryl-1,3,4-thiadiazolo-thiadiazolines (X).Cyclisation of VIII in the presence of other oxidising agents also leads to X.
