1204501-38-1

Basic information

• Product Name: IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester
• Synonyms: IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester;7-Chloro-iMidazo[1,2-a]pyridine-2-carboxylic acid ethyl ester;7-Chloro-2-(ethoxycarbonyl)imidazo[1,2-a]pyridine
• CAS NO: 1204501-38-1
• Molecular Formula: C10H9ClN2O2
• Molecular Weight: 224.64366
• Mol File: 1204501-38-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 177-179℃
• Appearance: /
• Density: 1.36±0.1 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 1.69±0.50(Predicted)
• CAS DataBase Reference: IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester(1204501-38-1)
• EPA Substance Registry System: IMidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester(1204501-38-1)

Safety Data

• Hazardous Substances Data: 1204501-38-1(Hazardous Substances Data)

Usage

General Description

"Imidazo[1,2-a]pyridine-2-carboxylic acid, 7-chloro-, ethyl ester" is a chemical compound. As suggested by its name, it's an ester derived from the reaction of 7-chloroimidazo[1,2-a]pyridine-2-carboxylic acid and ethanol. This chemical belongs to the class of organic compounds known as imidazo[1,2-a]pyridines, which are compounds containing an imidazo[1,2a]pyridine moiety, which is a pyridine fused to an imidazole ring. Specific information regarding its uses, properties or safety is not readily available, indicating it may be a niche or lesser-known compound.

Upstream product

• 1383080-55-4 ethyl 7-chloroimidazo[1,2-a]pyridine-2-carboxylate hydrobromide 
• 19798-80-2 2-Amino-4-chloropyridine 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 1020038-42-9 7-chloro-imidazo[1,2-a]pyridine-2-carboxylic acid 
• 1296200-01-5 N-(3-methoxybenzyl)-7-(1H-pyrazol-4-yl)imidazo[1,2-a]pyridine-2-carboxamide 
• 1296201-67-6 7-chloro-N-(3-methoxybenzyl)imidazo[1,2-a]pyridine-2-carboxamide 

Relevant articles and documents

IMIDAZOPYRIDINES AS RESPIRATORY SYNCYTIAL VIRUS ANTIVIRAL AGENTS

A compound satisfying formula I, a prodrug, N-oxide, addition salt, quaternary amine, metal complex, or a stereochemically isomeric form thereof; compositions contain these compounds as active ingredient and processes for preparing these compounds and compositions.

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: Exploration of 5-6 fused rings as alternative S1 moieties

A series of cis-1,2-diaminocyclohexane derivatives were synthesized with the aim of optimizing previously disclosed factor Xa (fXa) inhibitors. The exploration of 5-6 fused rings as alternative S1 moieties resulted in two compounds which demonstrated improved solubility and reduced food effect compared to the clinical candidate, compound A. Herein, we describe the synthesis and structure-activity relationship (SAR), together with the physicochemical properties and pharmacokinetic (PK) profiles of some prospective compounds.