1204501-40-5

Basic information

• Product Name: ethyl 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
• Synonyms: ethyl 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate
• CAS NO: 1204501-40-5
• Molecular Weight: 364.809
• Mol File: 1204501-40-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(1204501-40-5)
• EPA Substance Registry System: ethyl 5-chloro-1-(phenylsulfonyl)-1H-pyrrolo[2,3-c]pyridine-2-carboxylate(1204501-40-5)

Safety Data

• Hazardous Substances Data: 1204501-40-5(Hazardous Substances Data)

Upstream product

• 1204501-41-6 5-chloro-1-(benzenesulfonyl)-1H-pyrrolo[2,3-c]pyridine 
• 541-41-3 chloroformic acid ethyl ester 

Relevant articles and documents

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part I: Exploration of 5-6 fused rings as alternative S1 moieties

A series of cis-1,2-diaminocyclohexane derivatives were synthesized with the aim of optimizing previously disclosed factor Xa (fXa) inhibitors. The exploration of 5-6 fused rings as alternative S1 moieties resulted in two compounds which demonstrated improved solubility and reduced food effect compared to the clinical candidate, compound A. Herein, we describe the synthesis and structure-activity relationship (SAR), together with the physicochemical properties and pharmacokinetic (PK) profiles of some prospective compounds.