1204742-76-6

Basic information

• Product Name: Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester
• Synonyms: Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester;IMidazo[1,2-a]pyridine, 6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)-;MFCD13181965;6-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)H-imidazo[1,2-a]pyridine
• CAS NO: 1204742-76-6
• Molecular Formula: C13H17BN2O2
• Molecular Weight: 244.09728
• Product Categories: Organic boronic acid
• Mol File: 1204742-76-6.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• Density: 1.12±0.1 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 6.81±0.50(Predicted)
• CAS DataBase Reference: Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester(1204742-76-6)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine-6-boronic acic pinacol ester(1204742-76-6)

Safety Data

• Hazardous Substances Data: 1204742-76-6(Hazardous Substances Data)

Usage

Description

Imidazo[1,2-a]pyridine-6-boronic acid pinacol ester is an organic compound that serves as a key intermediate in the synthesis of various biologically active molecules, particularly those with potential applications in the pharmaceutical industry. It is characterized by its unique chemical structure, which includes an imidazo[1,2-a]pyridine core and a boronic acid pinacol ester functional group.

Uses

Used in Pharmaceutical Industry:
Imidazo[1,2-a]pyridine-6-boronic acid pinacol ester is used as a reagent for the preparation of Fatty Acid Synthase (FASN) inhibitors. These inhibitors are valuable in the treatment of various diseases, including cancer, due to their ability to disrupt the synthesis of fatty acids, which are essential for the growth and survival of cancer cells.
The compound's role in the development of FASN inhibitors highlights its potential as a therapeutic agent in the fight against cancer and other diseases. By targeting the fatty acid synthesis pathway, Imidazo[1,2-a]pyridine-6-boronic acid pinacol ester-based inhibitors can help to limit the proliferation of cancer cells and improve the effectiveness of existing treatments.

Upstream product

• 1072-97-5 5-bromo-2-pyridylamine 
• 73183-34-3 bis(pinacol)diborane 
• 827614-64-2 2-aminopyridine-5-boronic acid pinacol ester 
• 107-20-0 2-chloroethanal 
• 6188-23-4 6-bromoimidazo[1,2-a]pyridine 

Downstream Products

• 885275-62-7 imidazo[1,2-a]pyridine-6-ol 

Relevant articles and documents

INHIBITORS OF RECEPTOR INTERACTING PROTEIN KINASE I FOR THE TREATMENT OF DISEASE

Disclosed herein are compounds which inhibit RIPK1, pharmaceutical compositions, and methods of treatment of RIPK1-mediated diseases, such as neurodegenerative disorders, inflammatory disorders, and cancer.

Transition metal complex, polymer, mixture, composition and organic electronic device

The invention discloses a transition metal complex, a polymer, a mixture, a composition and an organic electronic device. The transition metal complex has a structural general formula represented by achemical formula (1), and is simple to synthesize, novel in structure, relatively good in stability, long in service life and good in light emitting performance; the compound represented by the chemical formula (1) is convenient for realizing an efficient, high-brightness and high-stability OLED device, and a relatively good material option is provided for full-color display and illumination application.

NOVEL BIARYL DERIVATIVE AND PHARMACEUTICAL USE THEREOF

PROBLEM TO BE SOLVED: To provide an agent for preventing and/or treating disease associated with group II mGlu receptor. SOLUTION: The present invention provides a compound of formula (1) or a pharmaceutically acceptable salt thereof (R1, Rsup