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1204809-96-0

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1204809-96-0 Usage

Description

2-(6-Phenylpyridin-3-yl)acetonitrile, also known as SGI-1027, is a chemical compound with the molecular formula C16H11N. It is a potent and selective inhibitor of the histone methyltransferase enzyme G9a, which is involved in gene regulation and implicated in various diseases, including cancer and neurological disorders.

Uses

Used in Pharmaceutical Industry:
2-(6-Phenylpyridin-3-yl)acetonitrile is used as a therapeutic agent for cancer treatment. It has shown promising results in preclinical studies by inhibiting the histone methyltransferase enzyme G9a, which plays a role in gene regulation and is implicated in cancer development.
Used in Research Applications:
2-(6-Phenylpyridin-3-yl)acetonitrile is used as a tool compound for studying the molecular mechanisms of histone methylation. Its ability to selectively inhibit the G9a enzyme makes it a valuable research tool for understanding the role of histone methylation in gene regulation and its implications in various diseases.
Used in Epigenetic Regulation:
2-(6-Phenylpyridin-3-yl)acetonitrile is being investigated for its potential role in epigenetic regulation. Its ability to inhibit the G9a enzyme suggests that it may have applications in modulating gene expression and treating diseases related to epigenetic dysregulation.

Check Digit Verification of cas no

The CAS Registry Mumber 1204809-96-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,4,8,0 and 9 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1204809-96:
(9*1)+(8*2)+(7*0)+(6*4)+(5*8)+(4*0)+(3*9)+(2*9)+(1*6)=140
140 % 10 = 0
So 1204809-96-0 is a valid CAS Registry Number.

1204809-96-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-(6-phenylpyridin-3-yl)acetonitrile

1.2 Other means of identification

Product number -
Other names (6-PHENYL-PYRIDIN-3-YL)-ACETONITRILE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1204809-96-0 SDS

1204809-96-0Relevant articles and documents

FUSED TRICYCLIC INHIBITORS OF MAMMALIAN TARGET OF RAPAMYCIN

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Page/Page column 37-38, (2012/04/23)

This invention relates to novel fused tricyclic compounds that are inhibitors of mammalian Target of Rapamycin (mTOR) kinase which is also known as FRAP, RAFT, RAPT or SEP, and are useful in the treatment of cellular proliferative diseases for example can

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