120505-35-3

Upstream product

• 109613-59-4 (S)-1-(benzyloxy)but-3-en-2-ol 
• 119046-49-0 (E)-1-Benzyloxy-4-trimethylsilanyl-but-3-en-2-ol 
• 119180-87-9 (2S,3E)-1-(benzyloxy)-4-(trimethylsilyl)but-3-en-2-ol 
• 120575-87-3 (R)-2-Benzyloxy-1-((2R,3R)-3-trimethylsilanyl-oxiranyl)-ethanol 
• 60656-87-3 benzyloxyacetoaldehyde 
• 14593-43-2 benzyl allyl ether 
• 114826-56-1 ((S)-1-Benzyloxymethyl-allyloxy)-tert-butyl-dimethyl-silane 

Relevant academic research and scientific papers

Total Synthesis of Pestalotioprolide e and Structural Revision of Pestalotioprolide F

A short and convergent strategy for the first asymmetric total synthesis of cytotoxic macrolides pestalotioprolides E and F has been developed. The key features of this synthesis include Takai olefination, Sonogashira coupling, Ni-assisted partial hydroge

A Practical Synthesis of Several Polyhydroxylated Chiral Building Blocks

A practical method for the synthesis of several useful polyhydroxylated chiral building blocks has been developed.The key reaction is the kinetic resolution of (E)-1-trimethylsilyl-4-alkoxy-1-buten-3-ol or (E)-1-trimethylsilyl-5-alkoxy-1-penten-3-ol using the Sharpless asymmetric epoxidation reaction.