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120511-73-1

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Product FOB Price Min.Order Supply Ability Supplier
Anti Estrogen Steroids Anastrozole/ Arimidex for bodybuilding
Cas No: 120511-73-1
No Data 10 Metric Ton Metric Ton/Day Hubei God bull Pharmaceutical Co.,Ltd Contact Supplier
High Purity Anastrozole Arimidex Steroid Hormone
Cas No: 120511-73-1
No Data 1 Kilogram 500~1000 Kilogram/Month Hubei Jusheng Technology Co., Ltd., Contact Supplier
Hot sales mdpt factory supply
Cas No: 120511-73-1
No Data 10 Gram 300 Kilogram/Month Wuhan New-Rise Biochem Co,. Ltd Contact Supplier
Supply high purity Anastrozole Arimidex 1mg tablet and raw material fast delivery
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No Data 1 Kilogram 1 Metric Ton/Month Shaanxi Mingqi Chemical Co., Ltd Contact Supplier
Anastrozole
Cas No: 120511-73-1
No Data 10 Gram 10 Kilogram/Day biochem-lab.org Contact Supplier
Anti Estrogen Steroids Anastrozole / Arimidex CAS NO 120511-73-1
Cas No: 120511-73-1
No Data 10 Gram 1000 Kilogram/Month Shanghai Taigui Pharmaceutical Technology Co., Ltd Contact Supplier
Anastrozole with 99.85% USP34 and good price
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USD $ 9.9-9.9 / Gram 10 Gram 50 Kilogram/Month FOND EVER CO.,LIMITED Contact Supplier
Factory direct Arimidex Anatrozole;Top purity/lowest price
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USD $ 1.0-1.0 / Gram 1 Gram 100 Kilogram/Day Theta biotechnology CO.,LTD Contact Supplier
Anastrozole CAS:120511-73-1
Cas No: 120511-73-1
No Data 1 Gram 1-100 Kilogram/Month Hangzhou Hysen Pharma co.,Ltd. Contact Supplier
arimidex Anastrolozole CAS:120511-73-1
Cas No: 120511-73-1
USD $ 1.0-1.0 / Gram 1 Gram 100 Kilogram/Day Guangzhou XinKe Chemical Co., LTD Contact Supplier

120511-73-1 Usage

Uses

antiseptic, spermaticide

Definition

ChEBI: A 1,2,4-triazole compound having a 3,5-bis(2-cyano-2-propyl)benzyl group at the 1-position.

Indications and Usage

Anastrozole is a potent selective triazole aromatase inhibitor that inhibits the aromatase that cytochrome P-450 is dependent on to prevent the biosynthesis of estrogen. Estrogen is the main stimulating factor for breast cancer cell growth. This drug’s half maximal inhibitory concentration (IC50) value to human placental aromatase is 15nmol/L. Compared to the traditional drug tamoxifen, Anastrozole can comprehensively and effectively lower the risks of breast cancer recurrence and metastasis, thus extending patients’ disease-free survival.
Anastrozole is suitable for treating postmenopausal advanced breast cancer patients, especially postmenopausal advanced breast cancer patients who experienced recurrence following hormone assisted therapy.

Clinical Research

A series of clinical trials compared the effects of third generation aromatase inhibitor Anastrozole with those of tamoxifen. The trial was a global multicenter trial and includes 381 centers in 21 countries. Since 1996, there have been 9366 patients who have participated, and the follow-up time is 100 months. 25.8% of patients in the Anastrozole group experienced recurrence, while 29.9% of patients in the tamoxifen group did. Thus, Anastrozole’s recurrence rate was 4.1% lower than that of tamoxifen, and its risk of distant metastasis was lower as well. Anastrozole is also safer than tamoxifen.

Brand name

Arimidex (AstraZeneca).

Chemical Properties

Crystalline Solid

Biological Activity

Potent and highly selective aromatase (CYP19) inhibitor (IC 50 = 15nM) that has no discernible effect on adrenocorticoid hormone synthesis. Reduces plasma estrogen levels and exhibits antitumor activity in vivo . Orally active.

Uses

An aromatase inhibitor. Used as an antineoplastic.
InChI:InChI=1S/C17H19N5/c1-16(2,9-18)14-5-13(8-22-12-20-11-21-22)6-15(7-14)17(3,4)10-19/h5-7,11-12H,8H2,1-4H3

120511-73-1 Well-known Company Product Price

Brand (Code)Product description CAS number Packaging Price Detail
Sigma (A2736)  Anastrozole  ≥98% (HPLC) 120511-73-1 A2736-50MG 3,473.73CNY Detail
Sigma (A2736)  Anastrozole  ≥98% (HPLC) 120511-73-1 A2736-10MG 872.82CNY Detail
USP (1034807)  Anastrozole  United States Pharmacopeia (USP) Reference Standard 120511-73-1 1034807-200MG 7,441.20CNY Detail
Sigma-Aldrich (Y0001522)  Anastrozole  European Pharmacopoeia (EP) Reference Standard 120511-73-1 Y0001522 1,880.19CNY Detail

120511-73-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name anastrozole

1.2 Other means of identification

Product number -
Other names ANASTRAZOLE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:120511-73-1 SDS

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