1205545-16-9Relevant academic research and scientific papers
Copper(II)/copper(I)-catalyzed aza-michael addition/click reaction of in situ generated α-azidohydrazones: Synthesis of novel pyrazolone-triazole framework
Attanasi, Orazio A.,Favi, Glanfranco,Filippone, Paolino,Mantellini, Fabio,Moscatelli, Giada,Perrulli, Francesca R.
supporting information; experimental part, p. 468 - 471 (2010/05/18)
[Chemical equaction presented] A one-pot Cu(II)-catalyzed aza-Michael addition of trlmethylsllyl azide to 1, 2-diaza-1, 3-dlenes and Cu(I)-catalyzed 1, 3-dipolar cycloaddition of in situ generated α-azidohydrazones with alkynes is reported. This process combining two consecutive steps with recycling of the catalyst (Cu(OAc)2-H2O) represents a useful protocol for the smooth synthesis of novel pyrazolone-trlazole derivatives.
