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1205548-01-1

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1205548-01-1 Usage

Chemical Properties

Off-white Crystalline Solid

Uses

4-(Dimethylamino)benzoic Acid 6-Acetyl-2,3-dimethoxyphenyl Ester is a reactant used in the preparation of 7,8-Dihydroxyflavone (D452830) derivatives which promote neurogenesis and exhibits potent antidepressant effect.

Check Digit Verification of cas no

The CAS Registry Mumber 1205548-01-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,5,5,4 and 8 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1205548-01:
(9*1)+(8*2)+(7*0)+(6*5)+(5*5)+(4*4)+(3*8)+(2*0)+(1*1)=121
121 % 10 = 1
So 1205548-01-1 is a valid CAS Registry Number.

1205548-01-1Relevant articles and documents

Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof

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Paragraph 26-28, (2018/03/25)

Novel compounds and methods related to the activation of the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of 7,8-dihydroxyflavone or derivative thereof. Specifically, methods and comp

A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect

Liu, Xia,Chan, Chi-Bun,Jang, Sung-Wuk,Pradoldej, Sompol,Huang, Junjian,He, Kunyan,Phun, Lien H.,France, Stefan,Xiao, Ge,Jia, Yonghui,Luo, Hongbo R.,Ye, Keqiang

experimental part, p. 8274 - 8286 (2011/02/23)

7,8-Dihydroxyflavone is a recently identified small molecular tropomyosin-receptor-kinase B (TrkB) agonist. Our preliminary structural-activity relationship (SAR) study showed that the 7,8-dihydroxy groups are essential for the agonistic effect. To improv

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