1205548-02-2

Basic information

• Product Name: 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione
• Synonyms: 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione
• CAS NO: 1205548-02-2
• Molecular Formula: C₁₉H₂₁NO₅
• Molecular Weight: 343.37374
• Product Categories: Agonist, Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1205548-02-2.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• Solubility: Dichloromethane, Methanol
• CAS DataBase Reference: 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione(1205548-02-2)
• EPA Substance Registry System: 1-[4-(DiMethylaMino)phenyl]-3-(2-hydroxy-3,4-diMethoxyphenyl)-1,3-propanedione(1205548-02-2)

Safety Data

• Hazardous Substances Data: 1205548-02-2(Hazardous Substances Data)

Usage

Chemical Properties

Yellow Solid

Uses

1-[4-(Dimethylamino)phenyl]-3-(2-hydroxy-3,4-dimethoxyphenyl)-1,3-propanedione is a reactant used in the preparation of 7,8-Dihydroxyflavone (D452830) derivatives which promote neurogenesis and exhibits potent antidepressant effect.

Upstream product

• 5396-18-9 2'-hydroxy-3',4'-dimethoxyacetophenone 
• 4755-50-4 4-(dimethylamino)benzoyl chloride 
• 1205548-01-1 6-acetyl-2,3-dimethoxyphenyl 4-(dimethylamino)benzoate 

Downstream Products

• 1205548-03-3 2-(4-(dimethylamino)phenyl)-7,8-dimethoxy-4H-chromen-4-one 

Relevant articles and documents

Treating various disorders with 7,8-dihydroxyflavone and derivatives thereof

Novel compounds and methods related to the activation of the TrkB receptor are provided. The methods include administering in vivo or in vitro a therapeutically effective amount of 7,8-dihydroxyflavone or derivative thereof. Specifically, methods and comp

A synthetic 7,8-dihydroxyflavone derivative promotes neurogenesis and exhibits potent antidepressant effect

7,8-Dihydroxyflavone is a recently identified small molecular tropomyosin-receptor-kinase B (TrkB) agonist. Our preliminary structural-activity relationship (SAR) study showed that the 7,8-dihydroxy groups are essential for the agonistic effect. To improv