120563-77-1Relevant academic research and scientific papers
STEROIDAL N-NITROAMINES. PART 4. INTRAMOLECULAR FUNCTIONALIZATION OF N-NITROAMINE RADICALS: SYNTHESIS OF 1,4-NITROIMINE COMPOUNDS
Armas, Pedro De,Francisco, Cosme G.,Hernandez, Rosendo,Salazar, Jose A.,Suarez, Ernesto
, p. 3255 - 3266 (2007/10/02)
Photolysis of 6β-nitroamino-5α-cholestane (4), 6β-nitroamino-5α-cholestane-3β-yl acetate (5), 2β-nitroamino-5α-cholestane (13), 4β-nitroamino-5α-cholestane (17), (20R)-20 nitroaminopregm-5-en-3β-yl acetate (26), (20R)- (31) and (20S)- (34)-nitroamino-5α-pregnan-3β-yl acetate, (23R,25S)-3β-acetoxy-23-nitroamino-5β-spirostan (46), 3β-nitroaminofriedelane (53), and methyl 3β-nitroaminofriedelan-29-oate (54) in the presence of iodine and various oxidative reagents leads to neutral nitroaminyl radicals which undergo intramolecular hydrogen-abstraction to produce in most cases N-nitroimine compounds.Best results were obtained with the system iodine and (diacetoxyiodo)benzene.
