1205665-82-2Relevant academic research and scientific papers
Design, synthesis and evaluation of aspirin analogues having an additional carboxylate substituent for antithrombotic activity
Alagha, Ahmed,Moman, Edelmiro,Adamo, Mauro F.A.,Nolan, Kevin B.,Chubb, Anthony J.
supporting information; experimental part, p. 4213 - 4216 (2010/04/29)
Acetylsalicylic acid (aspirin) is an effective long-term prophylaxis of thrombotic events such as heart attacks and strokes. It covalently inhibits prostaglandin-H-synthase by interacting with Arg120 or Tyr385 at the active site allowing delivery of its a
