120568-76-5Relevant academic research and scientific papers
Cyclization of 1-bromo-2,7- and 1-bromo-2,8-enynes mediated by indium
Lee, Phil Ho,Kim, Sundae,Lee, Kooyeon,Seomoon, Dong,Kim, Hyunseok,Lee, Seokju,Kim, Misook,Han, Mijeong,Noh, Kwanghyun,Livinghouse, Tom
, p. 4825 - 4828 (2004)
(Chemical Equation Presented) The cyclization of 1-bromo-2,7- and 1-bromo-2,8-enynes mediated by indium in DMF produced five- and six-membered cyclic compounds. Although KI was a necessary additive in the cyclization of terminal 1-bromo-2,7-enynes to give the desired products at 25°C, reactions of terminal 1-bromo-2,8-enynes and internal 1-bromo-2,7-enynes with indium proceeded at 100°C in DMF without KI. After cyclizations, subsequent cross-coupling reaction and iodolysis increase the usefulness of this reaction.
Rhodium(I)-Ctalyzed 'Metallo-Ene' Cyclizations/β-Eliminations
Oppolzer, Wolfgang,Fuerstner, Alois
, p. 2329 - 2337 (2007/10/02)
Octadienyl carbonates 5 provide cyclic 1,4-dienes 6 when treated with RhI complexes (1-10 mol-percent) at 80 deg C.Similar cyclization of cyclohexenyl acetate 8 affords cis-fused hexahydroindene 9.Analogues ring closures of nonadiene carbonate 10 yield preferably the cis-divinylpyrrolidine 11 with RhI catalysis but the trans-isomer 12 when catalyzed by Pd0.Azaoctadienyl carbonate 5a undergoes elimination with (5 mol-percent, 80 deg C) in MeCN giving acyclic triene 7.
SYNTHESIS OF NITROGEN- OR OXYGEN- CONTAINING RING SYSTEMS BY PALLADIUM-CATALYZED INTRAMOLECULAR OLEFIN ALLYLATIONS
Oppolzer, W.,Gaudin, J.-M.,Bedoya-Zurita, M.,Hueso-Rodriguez, J.,Raynham, T. M.,Robyr, C.
, p. 4709 - 4712 (2007/10/02)
Pd(PPh3)4-catalyzed cyclizations of N-allyl(crotyl, or 3-butenyl),N-butenyloxy derivatives and of an allyl(2-butenyloxy) ether give pyrrolidines, piperidines and a tetrahydrofuran in good yields.Hexahydroindoles and octahydroquinolines are thus obtained f
