120589-81-3

Basic information

• Product Name: benzyl 2(1H)-quinoxalinone-1-acetate
• Synonyms: benzyl 2(1H)-quinoxalinone-1-acetate
• CAS NO: 120589-81-3
• Molecular Weight: 294.31
• Mol File: 120589-81-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl 2(1H)-quinoxalinone-1-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl 2(1H)-quinoxalinone-1-acetate(120589-81-3)
• EPA Substance Registry System: benzyl 2(1H)-quinoxalinone-1-acetate(120589-81-3)

Safety Data

• Hazardous Substances Data: 120589-81-3(Hazardous Substances Data)

Upstream product

• 59564-59-9 1,2,3,4-tetrahydroquinoxalin-2-one 
• 140-18-1 Benzyl chloroacetate 
• 4937-77-3 4-(phenylsulfonyl)-3,4-dihydroquinoxalin-2(1H)-one 

Downstream Products

• 115699-68-8 4-benzenesulfonyl-3,4-dihydro-2(1H)-quinoxalinone-1-acetic acid 

Relevant articles and documents

Synthesis and aldose reductase inhibitory activity of N-1,N-4-disubstituted 3,4-dihydro-2(1H)-quinoxalinone derivatives

Synthetic routes have been developed for the preparation of 4-acylated, 4-benzenesulfonylated, and 4-methylated 3,4-dihydro-2(1H)-quinoxalinone-1-acetic acids. One example of the corresponding propionic acid has also been made. These compounds have been evaluated for their ability to inhibit bovine lens aldose reductase in vitro. Some members from this series also show weak activity in vivo, inhibiting sorbitol formation in sciatic nerves of streptozotocin-diabetic rats.