120602-97-3Relevant academic research and scientific papers
Differential Effects of a Series of Hydroxamic Acid Derivatives on 5-Lipoxygenase and Cyclooxygenase from Neutrophils and 12-Lipoxygenase from Platelets and Their in Vivo Effects on Inflammation and Anaphylaxis
Huang, Fu-Chih,Shoupe, T. Scott,Lin, Clara J.,Lee, Thomas D. Y.,Chan, Wan-Kit,et al.
, p. 1836 - 1842 (2007/10/02)
The synthesis of a series of novel substituted hydroxamates has been described along with their profile of inhibitory activity against 5-lipoxygenase, 12-lipoxygenase, and cyclooxygenase enzymes.The structure-activity relationship suggests that future mol
Quinoline hydroxamates and their use as modulators of arachidonic acid metabolic pathways
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, (2008/06/13)
This invention relates to new chemical compounds possessing valuable pharmaceutical activity, particularly as lipoxygenase inhibitors possessing anti-inflammatory and anti-allergic properties.
