1206163-59-8

Basic information

• Product Name: N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
• Synonyms: N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide
• CAS NO: 1206163-59-8
• Molecular Formula: C₁₇H₁₅BrN₄O
• Molecular Weight: 371.2312
• Mol File: 1206163-59-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• Density: 1.63±0.1 g/cm3(Predicted)
• PKA: 8.00±0.20(Predicted)
• CAS DataBase Reference: N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide(1206163-59-8)
• EPA Substance Registry System: N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide(1206163-59-8)

Safety Data

• Hazardous Substances Data: 1206163-59-8(Hazardous Substances Data)

Usage

General Description

N-(5-(4-(bromomethyl)phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide, also known as BPTU, is a chemical compound with potential pharmaceutical applications. Its molecular structure consists of a cyclopropane ring attached to a carboxamide group, with a triazolopyridine ring and a bromomethylphenyl group linked to the nitrogen and carbon atoms of the cyclopropane ring, respectively. BPTU is a promising candidate for the development of new drugs due to its ability to modulate specific biological targets, making it a potentially valuable compound in the field of medicinal chemistry. Further research is needed to fully understand the potential applications and effects of this chemical.

Upstream product

• 5720-05-8 4-methylphenylboronic acid 
• 1142936-90-0 N-[5-(4-methylphenyl)-[1,2,4]trithiazole[1,5-a]pyridin-2-yl]cyclopropanecarboxamide 
• 1142943-96-1 cyclopropanecarboxylic acid (5-bromo-[1,2,4]triazolo[1,5-a]pyridin-2-yl)-amide 
• 1010120-55-4 5-Bromo-[1,2,4]Triazolo[1,5-a]pyridine-2-ylamine 
• 1010120-59-8 ethyl N-[(6-bromopyridin-2-yl)carbamothioyl]carbamate 
• 19798-81-3 2-Amino-6-bromopyridine 
• 1142936-49-9 cyclopropanecarboxylic acid [5-(4-hydroxymethyl-phenyl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-amide 

Downstream Products

• 1206161-97-8 N-(5-{4-[(1,1-dioxo-1λ⁶-thiomorpholin-4-yl)methyl]phenyl}-[1,2,4]triazolo[1,5-a]pyridin-2-yl)cyclopropanecarboxamide 

Relevant articles and documents

NOVEL PROCESS FOR THE PREPARATION OF FILGOTINIB AND INTERMEDIATES THEREOF

The present invention relates to a novel process for the preparation of filgotinib or a pharmaceutically acceptable salt and intermediates thereof which avoid Suzuki coupling reaction. (I)

[1,2,4]triazol[1,5-a]pyridine compound as well as preparation method and medical application thereof

The invention relates to a [1,2,4]triazol[1,5-a] pyridine compound as well as a preparation method and medical application thereof. Particularly, the invention relates to the compound shown in a general formula I, the preparation method of the compound, a

PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF INFLAMMATORY DISORDERS

The present invention discloses pharmaceutical compositions comprising: a compound according to Formula I: useful in the prophylaxis and/or treatment of inflammatory conditions, autoimmune diseases, proliferative diseases, allergy, transplant rejection, d