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5-(4-Iodophenyl)-1,3-oxazole is a chemical compound with the molecular formula C8H5INO and a molecular weight of 263.03 g/mol. It is a heterocyclic compound consisting of an oxazole ring fused with an iodophenyl group. 5-(4-Iodophenyl)-1,3-oxazole is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals due to its unique structure and reactivity. The presence of the iodine atom in the 4-position of the phenyl ring allows for further functionalization and substitution reactions, making it a valuable building block in organic chemistry. The compound is typically synthesized through a cyclization reaction involving an amide and an α-halo ketone, followed by the introduction of the iodine atom. It is important to handle 5-(4-Iodophenyl)-1,3-oxazole with care due to its potential reactivity and the presence of the halogen.

1206169-98-3

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1206169-98-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1206169-98-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,1,6 and 9 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1206169-98:
(9*1)+(8*2)+(7*0)+(6*6)+(5*1)+(4*6)+(3*9)+(2*9)+(1*8)=143
143 % 10 = 3
So 1206169-98-3 is a valid CAS Registry Number.

1206169-98-3Downstream Products

1206169-98-3Relevant academic research and scientific papers

Tandem cycloaddition-decarboxylation of α-keto acid and isocyanide under oxidant-free conditions towards monosubstituted oxazoles

Zhang, Ling-Juan,Xu, Mei-Chen,Liu, Jie,Zhang, Xian-Ming

, p. 73450 - 73453 (2016/08/18)

An efficient method, tandem [3 + 2] cycloaddition-decarboxylation of α-keto acid and isocyanide promoted by copper salt, has been developed. Under oxidant-free conditions, a series monosubstituted oxazoles have been constructed. Different from the traditional application of α-oxo acids as acyl surrogates, the elegant approach herein ingeniously avoids consuming excess oxidants.

New compounds, pharmaceutical compositions and uses thereof

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Page/Page column 49-50, (2012/09/05)

The invention relates to new compounds of the formula I to their use as medicaments, to methods for their therapeutic use and to pharmaceutical compositions containing them.

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