1206189-69-6

Basic information

• Product Name: C₇H₆⁽¹⁸⁾FNO₂
• Synonyms: C₇H₆⁽¹⁸⁾FNO₂
• CAS NO: 1206189-69-6
• Molecular Weight: 154.13
• Mol File: 1206189-69-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₇H₆⁽¹⁸⁾FNO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₇H₆⁽¹⁸⁾FNO₂(1206189-69-6)
• EPA Substance Registry System: C₇H₆⁽¹⁸⁾FNO₂(1206189-69-6)

Safety Data

• Hazardous Substances Data: 1206189-69-6(Hazardous Substances Data)

Upstream product

• 66947-54-4 3-(2-methyl-4-nitrophenyl)-1,2,3-oxadiazol-3-ium-5-olate 
• 102308-59-8 2-((2-methyl-4-nitrophenyl)amino)acetic acid 
• 99-52-5 2-methyl-4-nitro-benzenamine 
• 7149-70-4 2-bromo-5-nitrotoluene 
• 1425187-96-7 2-methyl-4-nitrophenyl (4'-nitrophenyl) sulfide 
• 70264-20-9 2-methyl-4-nitrophenyl (phenyl) sulfide 
• 1425187-93-4 2-methyl-4-nitrophenyl(4'-nitrophenyl)sulfoxide 
• 1425187-92-3 2-methyl-4-nitrophenyl(phenyl)sulfoxide 
• 1206189-58-3 2-methyl-4-nitroiodylbenzene 

Relevant articles and documents

Synthesis of [18F]Fluoroarenes by Nucleophilic Radiofluorination of N-Arylsydnones

A practical method for radiofluorination of anilines with [18F]fluoride via N-arylsydnone intermediates is described. These precursors are stable, easy to handle and facilitate direct and regioselective 18F-labeling to prepare [

NUCLEOPHILIC FLUORINATION OF AROMATIC COMPOUNDS

Iodylbenzene derivatives substituted with electron donating as well as electron withdrawing groups on the aromatic ring are used as precursors in aromatic nucleophilic substitution reactions. The iodyl group (IO2) is regiospecifically substituted by nucleophilic fluoride to provide the corresponding fluoroaryl derivatives. No-carrier-added [F-18] fluoride ion derived from anhydrous [F- 18]KF/Kryptofix, [F-18]CsF or a quaternary ammonium fluoride (e.g., Me4NF, Et4NF, n-Bu4NF, (PhCH2)4NF) exclusively substitutes the iodyl moiety in these derivatives and provides high specific activity F- 18 labeled fluoroaryl analogs. Iodyl derivatives of a benzothiazole analog and 6-iodyl-L-dopa derivatives have been synthesized as precursors and have been used in the preparation of no-carrier-added [F-18]fluorobenzothiazole as well as 6-[F-18]fluoro-L-dopa.