1206626-36-9Relevant articles and documents
Copper-catalyzed tandem synthesis of [1,2,3]triazolo[5,1-a]isoquinolines and their transformation to 1,3-disubstituted isoquinolines
Hu, Yuan-Yuan,Hu, Jie,Wang, Xiang-Chuan,Guo, Li-Na,Shu, Xing-Zhong,Niu, Yan-Ning,Liang, Yong-Min
, p. 80 - 86 (2010)
2-Azido-3-(2-iodophenyl)acrylates react with terminal alkynes in the presence of a copper(II) catalyst without ligands to give a wide range of [1,2,3]triazolo[5,1-a]isoquinolines in good yields. These compounds favor expulsion of N2 in refluxed acetic acid to form 1,3-disubstituted isoquinolines. The procedure is simple, economical, and efficient.