120666-35-5Relevant articles and documents
Synthesis and Tubulin-Binding Properties of Some AC- and ABC-Ring Analogues of Allocolchicine
Banwell, Martin G.,Cameron, Jennifer M.,Corbett, Madeline,Dupuche, Joseph R.,Hamel, Ernest,et al.
, p. 1967 - 1982 (2007/10/02)
Fourteen analogues of the powerful antimitotic agent allocolchicine (5) have been prepared and evaluated for their ability to prevent tubulin polymerization.The X-ray structure of one of the more active compounds, tricyc