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1206694-75-8

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1206694-75-8 Usage

General Description

The chemical compound "(E)-N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline" is an organic compound that consists of a fluorinated aniline ring attached to a benzylidene group. It is commonly used as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds. The (E) in its name denotes the configuration of the double bond in the benzylidene group, indicating that the substituents are on the opposite sides of the double bond. (E)-N-(4-(Benzyloxy)benzylidene)-4-fluoroaniline has potential applications in medicinal chemistry and material science due to its unique structure and properties.

Check Digit Verification of cas no

The CAS Registry Mumber 1206694-75-8 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,6,9 and 4 respectively; the second part has 2 digits, 7 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1206694-75:
(9*1)+(8*2)+(7*0)+(6*6)+(5*6)+(4*9)+(3*4)+(2*7)+(1*5)=158
158 % 10 = 8
So 1206694-75-8 is a valid CAS Registry Number.

1206694-75-8Relevant articles and documents

A new class of ezetimibe derivative and its preparation method (by machine translation)

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Paragraph 0036-0039; 0060-0062, (2019/03/08)

The present invention provides a new class of ezetimibe derivatives, characterized in that its structural formula as shown in formula I: The invention the ezetimibe derivatives improves the water-solubility of ezetimibe, more conducive to clinical use. (by machine translation)

Visible-Light Photocatalytic Synthesis of Amines from Imines via Transfer Hydrogenation Using Quantum Dots as Catalysts

Xi, Zi-Wei,Yang, Lei,Wang, Dan-Yan,Pu, Chao-Dan,Shen, Yong-Miao,Wu, Chuan-De,Peng, Xiao-Gang

, p. 11886 - 11895 (2018/09/25)

CdSe/CdS core/shell quantum dots (QDs) can be used as stable and highly active photoredox catalysts for efficient transfer hydrogenation of imines to amines with thiophenol as a hydrogen atom donor. This reaction proceeds via a proton-coupled electron transfer (PCET) from the QDs conduction band to the protonated imine followed by hydrogen atom transfer from the thiophenol to the α-aminoalkyl radical. This precious metal free transformation is easy to scale up and can be carried out by a one-pot protocol directly from aldehyde, amine, and thiophenol. Additional advantageous features of this protocol include a wide substrate scope, high yield of the amine products, extremely low catalyst loading (0.001 mol %), high turnover number (105), and the mild reaction conditions of using visible light or sun light at room temperature in neutral media.

METHOD FOR PRODUCING EZETIMIBE AND INTERMEDIATE THEREOF

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, (2017/03/08)

PROBLEM TO BE SOLVED: To provide a method for producing ezetimibe that is a cholesterol-lowering agent. SOLUTION: The present invention provides a method for producing ezetimibe (I) that generates intermediate (M1) and eliminates a protecting group. [R1 is a benzyl group and others, R2 is an ether protecting group such as a silyl ether protecting group]. SELECTED DRAWING: None COPYRIGHT: (C)2016,JPOandINPIT

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