1206707-52-9Relevant academic research and scientific papers
Ruthenium catalyzed directing group-free C2-selective carbenoid functionalization of indoles by α-aryldiazoesters
Chan, Wai-Wing,Yeung, Shing-Hin,Zhou, Zhongyuan,Chan, Albert S. C.,Yu, Wing-Yiu
, p. 604 - 607 (2010)
[Chemical equation presented] A directing group-free approach for C2-selective carbenoid functionalization of NH-indoles is presented. Using [RuCl2(p-cymene)]2 as catalyst and α-aryldiazoesters as carbenoid source, 2-alkylated indoles were obtained in up to 96% isolated yield. Similarly, a regioselective carbenoid functionalization of NH-pyrroles was also achieved.
