1206770-07-1

Basic information

• Product Name: (4S,5R,8R,9S,10R)-4-[4-(benzyloxy)phenyl]-8,9,10-trihydroxy-1,6-dioxaspiro[4.5]decan-2-one
• Synonyms: (4S,5R,8R,9S,10R)-4-[4-(benzyloxy)phenyl]-8,9,10-trihydroxy-1,6-dioxaspiro[4.5]decan-2-one
• CAS NO: 1206770-07-1
• Molecular Weight: 386.401
• Mol File: 1206770-07-1.mol

Chemical Properties

• CAS DataBase Reference: (4S,5R,8R,9S,10R)-4-[4-(benzyloxy)phenyl]-8,9,10-trihydroxy-1,6-dioxaspiro[4.5]decan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R,8R,9S,10R)-4-[4-(benzyloxy)phenyl]-8,9,10-trihydroxy-1,6-dioxaspiro[4.5]decan-2-one(1206770-07-1)
• EPA Substance Registry System: (4S,5R,8R,9S,10R)-4-[4-(benzyloxy)phenyl]-8,9,10-trihydroxy-1,6-dioxaspiro[4.5]decan-2-one(1206770-07-1)

Safety Data

• Hazardous Substances Data: 1206770-07-1(Hazardous Substances Data)

Upstream product

• 1206770-06-0 (4S,5R,8R,9R,10R)-4-[4-(benzyloxy)phenyl]-10-hydroxy-8,9-bis(triisopropylsilyloxy)-1,6-dioxaspiro[4.5]decan-2-one 

Downstream Products

• 1206770-08-2 (4S,5R,8R,9S,10R)-8,9,10-trihydroxy-4-(4-hydroxyphenyl)-1,6-dioxaspiro[4.5]decan-2-one 

Relevant articles and documents

Oxidative spirocyclisation routes towards the sawaranospirolides. Synthesis of ent-sawaranospirolides C and D

Two routes are described for the synthesis of the sawaranospirolides, stereoisomeric spirolactone ascorbigenins isolated from Chamaecyparis pisifera. Trapping of the keto enal formed by oxidation of a functionalised 2-(4-hydroxybutyl)furan affords a potential butenolide spiroacetal precursor to sawaranospirolides A and C. Alternatively, epoxidation of protected 3-(dihydropyran-2-yl)3-arylpropanoic acids results in spirolactonisation to generate ent-sawaranospirolide C; a related acid-mediated spirocyclisation gave access to ent-sawaranospirolide D. The Royal Society of Chemistry 2010.