1206898-40-9Relevant academic research and scientific papers
Efficient synthesis of (R)- and (S)-α-(hydroxymethyl)pyroglutamic acid esters from L-proline
Shinada, Tetsuro,Yoshida, Hiroki,Ohfune, Yasufumi
, p. 3751 - 3756 (2009)
An efficient synthesis of (R)- and (S)-α-(hydroxymethyl)pyroglutamic acid esters from L-proline has been achieved. Each step was carried out on a decagram scale to access the N-protected (R)-ester in a highly efficient manner (44% overall yield from a pro
