1206905-69-2Relevant academic research and scientific papers
Copper(I)-catalyzed decarboxylative coupling of propiolic acids with secondary amines and aldehydes
Ermolat'ev, Denis S.,Feng, Huangdi,Song, Gonghua,Van Der Eycken, Erik V.
, p. 5346 - 5350 (2014)
An efficient microwave-assisted synthesis of tertiary propargylamines has been developed by copper(I)-catalyzed decarboxylative A3-coupling reaction of an alkynylcarboxylic acid with a secondary amine and an aldehyde. A wide range of diversely substituted propargylamines could be synthesized in high yields. The optimal reaction conditions are also effective for 3-alkylpropiolic acids and for terminal propiolic acid. Copyright
Microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine, and an alkyne
Feng, Huangdi,Ermolat'Ev, Denis S.,Song, Gonghua,Van Der Eycken, Erik V
supporting information; experimental part, p. 7608 - 7613 (2011/11/12)
A novel and efficient microwave-assisted decarboxylative three-component coupling of a 2-oxoacetic acid, an amine, and an alkyne (OA2- coulpling) has been developed. This new multicomponent coupling constitutes an efficient approach for the syn
