1206971-05-2 Usage
Uses
Used in Pharmaceutical Industry:
6-Bromoindolizine-2-carboxylic acid is used as a building block for the synthesis of various biologically active molecules. Its unique structure allows for the creation of new compounds with potential therapeutic effects, contributing to the development of novel drugs and treatments for various diseases and conditions.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 6-bromoindolizine-2-carboxylic acid is utilized for the development of new drugs and therapeutics. Its structural properties enable researchers to explore its potential in modulating biological targets and pathways, leading to the discovery of innovative treatments for a wide range of medical needs.
Used in Chemical Research and Drug Discovery:
6-Bromoindolizine-2-carboxylic acid serves as a valuable tool in chemical research and drug discovery efforts. Its unique structural features provide a foundation for investigating new chemical reactions and mechanisms, as well as for designing and optimizing drug candidates with improved efficacy, selectivity, and safety profiles.
Check Digit Verification of cas no
The CAS Registry Mumber 1206971-05-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,0,6,9,7 and 1 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 1206971-05:
(9*1)+(8*2)+(7*0)+(6*6)+(5*9)+(4*7)+(3*1)+(2*0)+(1*5)=142
142 % 10 = 2
So 1206971-05-2 is a valid CAS Registry Number.
1206971-05-2Relevant articles and documents
2-indolizine Carbamoyl amine compound and its preparation and use
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Paragraph 0112; 0176-0179, (2020/02/07)
The invention discloses a novel 2-indolizine formylamine derivative. The general formula of the novel 2-indolizine formylamine derivative is as shown in a formula (I), wherein the definition of R is specified in the specification. In addition, the inventi
Synthesis and biological activities of indolizine derivatives as alpha-7 nAChR agonists
Xue, Yu,Tang, Jingshu,Ma, Xiaozhuo,Li, Qing,Xie, Bingxue,Hao, Yuchen,Jin, Hongwei,Wang, Kewei,Zhang, Guisen,Zhang, Liangren,Zhang, Lihe
, p. 94 - 108 (2016/04/05)
Human α7 nicotinic acetylcholine receptor (nAChR) is a promising therapeutic target for the treatment of schizophrenia accompanied with cognitive impairment. Herein, we report the synthesis and agonistic activities of a series of indolizine derivatives targeting to α7 nAChR. The results show that all synthesized compounds have affinity to α7 nAChR and some give strong agonistic activity, particularly most active agonists show higher potency than control EVP-6124. The docking and structure-activity relationship studies provide insights to develop more potent novel α7 nAChR agonists.
