1207069-46-2Relevant academic research and scientific papers
MACROLIDE COMPOUND HAVING ANTICANCER EFFECT
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, (2013/11/05)
The present invention relates to a macrolide compound expected to have a cell growth-inhibiting activity and a novel anticancer drug utilizing the compound. Specifically, the invention relates to a compound represented by Formula (I) or (II) or a pharmaceutically acceptable salt thereof and relates to a cell growth inhibitor and an anticancer drug each containing the compound or the salt as an active ingredient.
Total synthesis and biological assessment of (-)-Exiguolide and analogues
Fuwa, Haruhiko,Suzuki, Takaya,Kubo, Hiroshi,Yamori, Takao,Sasaki, Makoto
scheme or table, p. 2678 - 2688 (2011/04/15)
We describe herein an enantioselective total synthesis of (-)-exiguolide, the natural enantiomer. The methylene bis(tetrahydropyran) substructure was efficiently synthesized by exploiting olefin cross-metathesis for the assembly of readily available acycl
Total synthesis of (-)-exiguolide
Fuwa, Haruhiko,Sasaki, Makoto
supporting information; experimental part, p. 584 - 587 (2010/05/17)
[Chemical equation presented] Total synthesis of (-)-exiguolide, the natural enantiomer, has been accomplished for the first time. The bis(tetrahydropyran) subunit was efficiently synthesized via consecutive olefin cross-metathesis/intramolecular oxa-conj
