1207166-30-0

Basic information

• Product Name: (R)-2,2,2-trifluoro-N-(1-(2-(methyl)phenyl)ethyl)acetamide
• CAS NO: 1207166-30-0
• Molecular Weight: 231.218
• Mol File: 1207166-30-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-2,2,2-trifluoro-N-(1-(2-(methyl)phenyl)ethyl)acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-2,2,2-trifluoro-N-(1-(2-(methyl)phenyl)ethyl)acetamide(1207166-30-0)
• EPA Substance Registry System: (R)-2,2,2-trifluoro-N-(1-(2-(methyl)phenyl)ethyl)acetamide(1207166-30-0)

Safety Data

• Hazardous Substances Data: 1207166-30-0(Hazardous Substances Data)

Upstream product

• 407-25-0 trifluoroacetic anhydride 
• 577-16-2 2-Methylacetophenone 
• 35106-87-7 1-o-tolylethanamine hydrochloride 
• 42142-17-6 1-(o-tolyl)ethanamine 
• 194024-39-0 N-benzyl-1-(o-tolyl)ethan-1-amine 
• 1307727-86-1 1-phenyl-N-(1-(o-tolyl)ethylidene)methanamine 

Relevant articles and documents

Sequential reductive amination-hydrogenolysis: A one-pot synthesis of challenging chiral primary amines

Difficult-to-access chiral primary amines were formed in good to high yield and ee using a rare example of a one-pot synthesis from prochiral ketones (sequential reductive amination-hydrogenloysis). As a highlight we also demonstrate a one-pot reductive amination-hydrogenolysis-reductive amination (five reactions) of ortho-methoxyacetophenone resulting in the chiral diamine 1-(2-methoxyphenyl)ethyl-(2-pyridylmethyl)-amine (4) (58% overall yield, >99% ee), a new organocatalyst for aqueous enantioselective aldol reactions. Copyright