1207166-45-7

Basic information

• Product Name: 3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 14,20-dihydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester
• Synonyms: 3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 14,20-dihydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester
• CAS NO: 1207166-45-7
• Molecular Weight: 822.092
• Mol File: 1207166-45-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 14,20-dihydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 14,20-dihydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester(1207166-45-7)
• EPA Substance Registry System: 3-tert-butoxycarbonylamino-2-hydroxy-3-phenyl-propionic acid 14,20-dihydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester(1207166-45-7)

Safety Data

• Hazardous Substances Data: 1207166-45-7(Hazardous Substances Data)

Upstream product

• 373645-86-4 (5Z,13Z)-(2R,3R,4S,8S,9R,10R,11S,12S)-3,9-bis(tertbutyldimethylsilanyloxy)-11-hydroxy-2,4,6,8,10,12-hexamethylhexadeca-5,13,15-trienal 
• 1082395-61-6 C₄₈H₈₆O₇Si₂ 
• 1082395-55-8 C₄₅H₈₃IO₅Si₂ 
• 1082395-54-7 C₅₀H₈₅IO₆Si₂ 
• 1207166-37-7 14,20-bis(tert-butyl-dimethyl-silanyloxy)-8,10-dihydroxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-oxacyclodocosa-3,5,11,16-tetraen-2-one 
• 1082395-62-7 C₄₈H₈₄O₆Si₂ 
• 1266549-20-5 C₅₇H₁₀₈O₆Si₄ 
• 1207166-42-4 14,20-bis(tert-butyl-dimethyl-silanyloxy)-8-hydroxy-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-oxacyclodocosa-3,5,11,16-tetraen-2-one 
• 1207166-55-9 3-tert-butoxycarbonylamino-3-phenyl-2-triethylsilanyloxy-propionic acid 14,20-bis(tert-butyl-dimethyl-silanyloxy)-10-methoxy-7,13,15,17,19,21-hexamethyl-22-(1-methyl-penta-2,4-dienyl)-2-oxo-oxacyclodocosa-3,5,11,16-tetraen-8-yl ester 

Relevant articles and documents

Total synthesis of a library of designed hybrids of the microtubule-stabilising anticancer agents taxol, discodermolide and dictyostatin

A hybrid library of the marine natural products dictyostatin and discodermolide, incorporating the taxol or taxotere side chains, were synthesised; preliminary biological evaluation in the PANC-1 cancer cell line revealed significant antiproliferative activity, demonstrating that a macrolide scaffold is an effective surrogate for the baccatin core of taxol.