1207183-67-2Relevant academic research and scientific papers
Design and synthesis of potent Gram-negative specific LpxC inhibitors
Faruk Mansoor,Vitharana, Dilrukshi,Reddy, Panduranga Adulla,Daubaras, Dayna L.,McNicholas, Paul,Orth, Peter,Black, Todd,Arshad Siddiqui
, p. 1155 - 1161 (2011/04/16)
Antibiotic resistant hospital acquired infections are on the rise, creating an urgent need for novel bactericidal drugs. Enzymes involved in lipopolysaccharide (LPS) biosynthesis are attractive antibacterial targets since LPS is the major structural compo
UREA DERIVATIVES AS ANTIBACTERIAL AGENTS
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Page/Page column 35-36, (2010/04/03)
This invention relates to compounds of the Formula (I):or a pharmaceutically acceptable salt, solvate, ester or isomer thereof, which is useful for the treatment of diseases or conditions mediated by LpxC.
