1207202-67-2Relevant academic research and scientific papers
Desymmetrisation of: Meso -diones promoted by a highly recyclable polymer-supported chiral phosphoric acid catalyst
Clot-Almenara, Lidia,Rodríguez-Escrich, Carles,Pericàs, Miquel A.
, p. 6910 - 6914 (2018)
A polystyrene-supported BINOL-derived chiral phosphoric acid has been applied to the desymmetrisation of meso-diones to produce enantioenriched cyclohexenones. The catalytic resin has proven highly active and robust, giving rise to Hajos-Parrish or Wieland-Miescher type products in good yields and enantioselectivities, while allowing for extended recycling.
Chiral phosphoric acid catalyzed desymmetrization of meso-1,3diones: Asymmetric synthesis of chiral cyclohexenones
Mori, Keiji,Katoh, Takuya,Suzuki, Tohru,Noji, Takuya,Yamanaka, Masahiro,Akiyama, Takahiko
, p. 9652 - 9654 (2010/04/28)
Chiral effectiveness: The title transformation is applicable to a wide variety of substrates to give chiral cyclohexenones in high yields and with excellent enantioselecti vity (see scheme). To clarity the origin of the enantioselectivity ONIOM calculations were carried out
