1207202-75-2

Upstream product

• 1207203-48-2 1-{[4-(2,4-Dichlorophenyl)-5-(4-hydroxyphenyl)thien-2-yl]carbonyl}-4-phenylpiperidine-4-carboxamide 
• 627-30-5 1-chloro-3-hydroxypropane 
• 80139-80-6 4-carbamoyl-4-phenylpiperidine 
• 1207203-46-0 1-{[4-(2,4-Dichlorophenyl)-5-(4-methoxyphenyl)thien-2-yl]carbonyl}-4-phenylpiperidine-4-carboxamide 
• 1207203-47-1 4-(2,4-dichlorophenyl)-5-(4-methoxyphenyl)thiophene-2-carboxylic acid 

Downstream Products

• 1207203-51-7 3-(4-{5-[(4-Carbamoyl-4-phenylpiperidin-1-yl) carbonyl]-3-(2,4-dichlorophenyl)thien-2-yl}phenoxy)propyl methanesulphonate 
• 1207202-81-0 1-{[4-(2,4-Dichlorophenyl)-5-{4-[3-(methylthio)propoxy]phenyl}-thien-2-yl]carbonyl}-4-phenylpiperidine-4-carboxamide 
• 1207202-83-2 1-{[4-(2,4-dichlorophenyl)-5-{4-[3-(methylsulphonyl)propoxy]phenyl}-2-thienyl]carbonyl}-4-phenylpiperidine-4-carboxamide 

Relevant academic research and scientific papers

THIOPHENE-2-CARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF

The subject matter of the invention is compounds corresponding to formula (I), in which: R1 and R2, together with the nitrogen atom to which they are attached, constitute a saturated heterocyclic radical containing from 4 to 7 atoms, which is preferably substituted; one of the two substituents R3 and R6 is a group Y-A-R9; Y is an oxygen atom or an —S(O)n′—, or —OSO2 group; A is an unsubstituted (C1-C4) alkylene group; R9 is an —OR19, —CH3, —NR19R20, —CONR19R20, —NR15COR19, —S(O)nR21, or —NR13SO2R21 group; —R10 is a hydrogen atom or a (C1-C4) alkyl group. The present invention also relates to the methods of preparation and the therapeutic uses of the compounds of formula (I).