1207328-56-0

Basic information

• Product Name: 5-iodo-1-(4-nitrobenzyl)-4-phenyl-1H-1,2,3-triazole
• Synonyms: 5-iodo-1-(4-nitrobenzyl)-4-phenyl-1H-1,2,3-triazole
• CAS NO: 1207328-56-0
• Molecular Weight: 406.182
• Mol File: 1207328-56-0.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 5-iodo-1-(4-nitrobenzyl)-4-phenyl-1H-1,2,3-triazole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-iodo-1-(4-nitrobenzyl)-4-phenyl-1H-1,2,3-triazole(1207328-56-0)
• EPA Substance Registry System: 5-iodo-1-(4-nitrobenzyl)-4-phenyl-1H-1,2,3-triazole(1207328-56-0)

Safety Data

• Hazardous Substances Data: 1207328-56-0(Hazardous Substances Data)

Upstream product

• 932-88-7 1-iodo-2-phenylethyne 
• 17271-88-4 p-nitrobenzyl azide 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Catalytic and computational studies of N-heterocyclic carbene or phosphine-containing copper(I) complexes for the synthesis of 5-iodo-1,2,3-triazoles

Two complementary catalytic systems are reported for the 1,3-dipolar cycloaddition of azides and iodoalkynes. These are based on two commercially available/readily available copper complexes, [CuCl(IPr)] or [CuI(PPh 3)3], which are active at low metal loadings (PPh 3 system) or in the absence of any other additive (IPr system). These systems were used for the first reported mechanistic studies on this particular reaction. An experimental/computational-DFT approach allowed to establish that (1) some iodoalkynes might be prone to dehalogenation under copper catalysis conditions and, more importantly, (2) two distinct mechanistic pathways are likely to be competitive with these catalysts, either through a copper(III) metallacycle or via direct-activation of the starting iodoalkyne.

Method for synthesizing 5-I-1,2,3-triazole compound from multiple ingredients in water solution

The invention discloses a method for synthesizing 5-I-1,2,3-triazole compound from multiple ingredients in a water solution. According to the method, iodine-source tetraethyl ammonium iodide, oxidizing agent 1-chloromethyl-4-fluorin-1,4-diazotization bicy

Multicomponent Aqueous Synthesis of Iodo-1,2,3-triazoles: Single-Step Models for Dual Modification of Free Peptide and Radioactive Iodo Labeling

Iodo-1,2,3-triazoles are of considerable interest for chemical and biomedical applications. However, current synthetic methods for preparing iodo-1,2,3-triazoles cannot easily be applied to the direct modification of bioactive molecules in water. Through