1207371-88-7

Basic information

• Product Name: D-749848
• CAS NO: 1207371-88-7
• Molecular Weight: 481.96
• Mol File: 1207371-88-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: D-749848(CAS DataBase Reference)
• NIST Chemistry Reference: D-749848(1207371-88-7)
• EPA Substance Registry System: D-749848(1207371-88-7)

Safety Data

• Hazardous Substances Data: 1207371-88-7(Hazardous Substances Data)

Upstream product

• 99-76-3 methyl 4-hydroxylbenzoate 
• 5351-23-5 4-hydroxybenzoic acid hydrazide 
• 891572-42-2 C₁₆H₁₇N₃O₄S 
• 536-38-9 4-chlorobenzoylmethyl bromide 

Relevant articles and documents

Synthesis and antitumor activity of (4-hydroxyphenyl) [5-substituted alkyl/aryl)-2-thioxo-1,3,4-thiadiazol-3-yl]methanone and [(3,4-disubstituted)-1, 3-thiazol-2ylidene]- 4-hydroxybenzohydrazide

To examine new drug leads with potential anticancer activity, some (4-hydroxyphenyl)[5-substituted alkyl/aryl)-2-thioxo-1,3,4-thiadiazol-3-yl] methanone (4.a- 4.c) and [-(3,4-disubstituted)-1,3-thiazol-2ylidene)]-4- hydroxybenzohydrazide (6.a-6.d) were synthesized using appropriate synthetic route. The newly prepared compounds 4.a-4.c and 6.a-6.d demonstrated inhibitory effects on the growth of a wide range of cancer cell lines especially on leukemia (HL-60), non-small lung cancer (HOP- 92), renal cancer (ACHN) at the range of GI50 -4.23 to -7.23. Springer Science+Business Media, LLC 2010.