1207385-11-2Relevant academic research and scientific papers
Synthesis and Optical Properties of a Series of Green-Light-Emitting 2-(4-Phenylquinolin-2-yl)phenol-BF2 Complexes (Boroquinols)
Balijapalli, Umamahesh,Iyer, Sathiyanarayanan Kulathu
, p. 5089 - 5098 (2015)
A series of 2-(4-phenylquinolin-2-yl)phenol derivatives were efficiently synthesized and complexed with boron trifluoride to give fluorescent organoboron complexes. All the synthesized compounds were characterized by 1H, 13C, 11B, 19F NMR, FTIR, and HRMS analyses, and single-crystal structures of representative compounds were determined to examine the conformations of these compounds. The electronic properties of 2-(4-phenylquinolin-2-yl)phenol-BF2 complexes were studied by absorption and fluorescence spectroscopy and the complexes were found to be highly emissive in the solid state. The electrochemical properties of boroquinols were measured by using cyclic voltammetry (CV) in acetonitrile with 0.1 M tetrabutyl ammonium hexafluorophosphate as a supporting electrolyte and the LUMO values of boroquinols were calculated to range from -2.64 to -3.46 eV, with HOMO values of -5.32 to -6.10 eV.
Molecular explorations of substituted 2-(4-phenylquinolin-2-yl) phenols as phosphoinositide 3-kinase inhibitors and anticancer agents
Alagumuthu, Manikandan,Arumugam, Sivakumar
, p. 389 - 397 (2017)
Purpose: Substituted 2-(4-phenylquinolin-2-yl) phenols (PQPDs) emerged as the inhibitors of phosphoinositide 3-kinase (PI3K) and anticancer agents. Method: PI3K inhibition was assessed by competitive ELISA. Anticancer activity was evaluated against breast
Fast, solvent-free, microwave-promoted friedlaender annulation with a reusable solid catalyst
Garella, Davide,Barge, Alessandro,Upadhyaya, Dharita,Rodriguez, Zalua,Palmisano, Giovanni,Cravotto, Giancarlo
experimental part, p. 120 - 128 (2010/03/24)
A fast, solvent-free method is described for the synthesis of substituted quinoline derivatives via Friedlander cyclization, employing a reusable solid catalyst (silica-propylsulfonic acid). Although it worked best under microwave irradiation (with generally more than 90% isolated yields in 30min), the reaction was also feasible under conventional heating (with fair to good yields in about 5h).
