1207429-53-5

Basic information

• Product Name: 4-fluorophenyl 1H-imidazole-1-sulfonate
• Synonyms: 4-fluorophenyl 1H-imidazole-1-sulfonate
• CAS NO: 1207429-53-5
• Molecular Weight: 242.231
• Mol File: 1207429-53-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-fluorophenyl 1H-imidazole-1-sulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-fluorophenyl 1H-imidazole-1-sulfonate(1207429-53-5)
• EPA Substance Registry System: 4-fluorophenyl 1H-imidazole-1-sulfonate(1207429-53-5)

Safety Data

• Hazardous Substances Data: 1207429-53-5(Hazardous Substances Data)

Upstream product

• 371-41-5 4-Fluorophenol 
• 7189-69-7 N,N`-sulfuryldiimidazole 

Downstream Products

• 397-54-6 2-(4-fluorophenyl)benzoxazole 

Relevant articles and documents

Synthesis of 18F-Labeled Aryl Fluorosulfates via Nucleophilic Radiofluorination

Sulfuryl fluoride gas is a key reagent for SO2F transfer. However, conventional SO2F transfer reactions have limited 18F-radiochemistry translation, due to the inaccessibility of gaseous [18F]SO2F2. Herein, we report the first SO2F2-free synthesis of aryl [18F]fluorosulfates from both phenolic and isolated aryl imidazylate precursors with cyclotron-produced 18F-. The radiochemical yields ranged from moderate to good with excellent functional group tolerance. The reliability of our approach was validated by the automated radiosynthesis of 4-acetamidophenyl [18F]fluorosulfate.