120743-62-6

Basic information

• Product Name: (E)-5,6-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-oct-5-enoic acid [(2S,3S,4S,6R)-6-((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-amide
• Synonyms: (E)-5,6-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-oct-5-enoic acid [(2S,3S,4S,6R)-6-((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-amide
• CAS NO: 120743-62-6
• Molecular Weight: 1064.43
• Mol File: 120743-62-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (E)-5,6-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-oct-5-enoic acid [(2S,3S,4S,6R)-6-((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-amide(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-5,6-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-oct-5-enoic acid [(2S,3S,4S,6R)-6-((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-amide(120743-62-6)
• EPA Substance Registry System: (E)-5,6-Bis-[4-(tert-butyl-dimethyl-silanyloxy)-phenyl]-oct-5-enoic acid [(2S,3S,4S,6R)-6-((1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacen-1-yloxy)-3-hydroxy-2-methyl-tetrahydro-pyran-4-yl]-amide(120743-62-6)

Safety Data

• Hazardous Substances Data: 120743-62-6(Hazardous Substances Data)

Upstream product

• 23541-50-6 daunomycin hydrochloride 
• 120743-59-1 (E)-4-pentachlorophenyl 5,6-bis<4-(tert-butyldimethylsiloxy)phenyl>-5-octenoate 
• 67566-96-5 5,6-bis(4-hydroxyphenyl)-5-octenoic acid 
• 67566-95-4 5,6-bis(4-methoxyphenyl)-5-octenoic acid 
• 18162-48-6 tert-butyldimethylsilyl chloride 

Relevant articles and documents

Diethylstilbestrol-linked cytotoxic agents: Synthesis and binding affinity for estrogen receptors

The syntheses of diethylstilbestrol derivatives with a C4 side chain at the double bond bearing various functional and potentially alkylating groups (9-25, 38-40, 43-44) as well as the coupling product with daunorubicine (41) are described. Der