1207454-48-5

Basic information

• Product Name: (E)-4-(4-fluorobenzylideneamino)isobenzofuran-1(3H)-one
• Synonyms: (E)-4-(4-fluorobenzylideneamino)isobenzofuran-1(3H)-one
• CAS NO: 1207454-48-5
• Molecular Weight: 255.248
• Mol File: 1207454-48-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (E)-4-(4-fluorobenzylideneamino)isobenzofuran-1(3H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-4-(4-fluorobenzylideneamino)isobenzofuran-1(3H)-one(1207454-48-5)
• EPA Substance Registry System: (E)-4-(4-fluorobenzylideneamino)isobenzofuran-1(3H)-one(1207454-48-5)

Safety Data

• Hazardous Substances Data: 1207454-48-5(Hazardous Substances Data)

Upstream product

• 59434-19-4 4-Amino-1(3H)-isobenzofuranon 
• 459-57-4 4-fluorobenzaldehyde 
• 641-70-3 3-nitrophthalic acid anhydride 
• 65399-18-0 4-nitrophthalide 

Downstream Products

• 1207454-79-2 ethyl 3-(4,5-dimethyl-4H-1,2,4-triazol-3-yl)-2-(4-fluorophenyl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207455-19-3 ethyl 2-(4-fluorophenyl)-3-(4-methyl-4H-1,2,4-triazol-3-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207455-10-4 ethyl 3-(4-(dimethylcarbamoyl)phenyl)-2-(4-fluorophenyl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-47-4 ethyl 2-(4-fluorophenyl)-3-(1-methyl-1H-imidazol-2-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-91-8 ethyl 2-(4-fluorophenyl)-4-oxo-3-(thiazol-2-yl)-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207455-23-9 ethyl 2-(4-fluorophenyl)-3-(1-methyl-1H-imidazo[4,5-c]pyridin-2-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-93-0 ethyl 3-(1-ethyl-1H-imidazol-2-yl)-2-(4-fluorophenyl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-72-5 ethyl 2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-70-3 ethyl 2-(4-fluorophenyl)-4-oxo-3-(1,4,5-trimethyl-1H-imidazol-2-yl)-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207454-68-9 ethyl 2-(4-fluorophenyl)-3-(1-methyl-1H-1,2,4-triazol-5-yl)-4-oxo-1,2,3,4-tetrahydroquinoline-5-carboxylate 
• 1207455-22-8 8-(4-fluorophenyl)-9-(1-methyl-1H-imidazo[4,5-c]pyridin-2-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one 
• 1207455-09-1 4-(8-(4-Fluorophenyl)-3-oxo-3,7,8,9-tetrahydro-2H-pyrido[4,3,2-de]phthalazin-9-yl)-N,N-dimethylbenzamide 
• 1207455-99-9 (8S,9R)-8-(4-fluorophenyl)-9-(1-methyl-1H-imidazol-2-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one 
• 1207455-98-8 (8R,9S)-8-(4-fluorophenyl)-9-(1-methyl-1H-imidazol-2-yl)-8,9-dihydro-2H-pyrido[4,3,2-de]phthalazin-3(7H)-one 

Relevant articles and documents

METHODS OF USING DIHYDROPYRIDOPHTHALAZINONE INHIBITORS OF POLY (ADP-RIBOSE)POLYMERASE (PARP)

Provided herein are methods of treating cancer comprising administering a topoisomerase inhibitor, temozolomide, or a platin in combination with a Compound of Formula (I) or Formula (II), where the substituents Y, Z, A, B, R1, R2, R3, R4 and R5 are as defined herein.