1207459-97-9Relevant academic research and scientific papers
A straightforward synthesis of (S)-Anabasine via the catalytic, enantioselective vinylogous mukaiyama-Mannich reaction
Giera, David S.,Sickert, Marcel,Schneider, Christoph
experimental part, p. 3797 - 3802 (2010/03/26)
The tobacco alkaloid (S)-anabasine was synthesized by a straightforward 4-step sequence with the catalytic enantioselective vinylogous Mannich reaction as a key step. Only 3 mol% of a structurally optimized chiral BINOL-based phosphoric acid was employed to control the absolute configuration of the natural product. Georg Thieme Verlag Stuttgart.
