1207552-65-5

Basic information

• Product Name: 5-tert-butyl-6-chloro-N-(2-bromo-3-methylphenyl)pyrazine-2-carboxamide
• CAS NO: 1207552-65-5
• Molecular Weight: 382.687
• Mol File: 1207552-65-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-tert-butyl-6-chloro-N-(2-bromo-3-methylphenyl)pyrazine-2-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: 5-tert-butyl-6-chloro-N-(2-bromo-3-methylphenyl)pyrazine-2-carboxamide(1207552-65-5)
• EPA Substance Registry System: 5-tert-butyl-6-chloro-N-(2-bromo-3-methylphenyl)pyrazine-2-carboxamide(1207552-65-5)

Safety Data

• Hazardous Substances Data: 1207552-65-5(Hazardous Substances Data)

Upstream product

• 54879-20-8 2-bromo-3-methylaniline 
• 879131-25-6 6-chloro-5-tert-butylpyrazine-2-carboxylic acid chloride 

Relevant articles and documents

Substituted N-phenylpyrazine-2-carboxamides: Synthesis and antimycobacterial evaluation

The condensation of chlorides of substituted pyrazinecarboxylic acids with ringsubstituted anilines yielded twelve substituted pyrazinecarboxylic acid amides. The synthetic approach, analytical, and lipophilicity data of the newly synthesized compounds are presented. Two antituberculosis assays were used. Firstly, the antimycobacterial activity against four different Mycobacterium strains in a series of pyrazine derivatives was investigated. Secondly, the antimycobacterial evaluation was performed at the Tuberculosis Antimicrobial Acquisition and Coordinating Facility (TAACF) program. Interesting in vitro antimycobacterial activity was found, N-(3-iodo-4-methylphenyl) pyrazine-2-carboxamide (9) was most active derivative compound against M. tuberculosis (MIC 90 = 0.819 μg/mL).