1207601-60-2Relevant academic research and scientific papers
NOVEL TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
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Paragraph 00446-00447, (2013/10/22)
The present invention relates to novel triazole Hsp90 inhibitors that possess significant inhibitory activity against Hsp90, which are suitable for the treatment of hyperproliferative diseases such as cancer, infections, immune disorders, inflammation, and CNS related disorders. Furthermore, pharmaceutical compositions, including combination products, are also provided in the present application. Further provided are methods of using the pharmaceutical compositions and/or combination products.
TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY
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Page/Page column 174, (2010/05/13)
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a pharmaceutical composition comprising such a compound.
