1207673-22-0Relevant articles and documents
Synthesis and investigation of polyhydroxylated pyrrolidine derivatives as novel chemotypes showing dual activity as glucosidase and aldose reductase inhibitors
Guazzelli, Lorenzo,D'Andrea, Felicia,Sartini, Stefania,Giorgelli, Francesco,Confini, Gianluca,Quattrini, Luca,Piano, Ilaria,Nencetti, Susanna,Orlandini, Elisabetta,Gargini, Claudia,La Motta, Concettina
, (2019)
Diabetes is a multi-factorial disorder that should be treated with multi-effective compounds. Here we describe the access to polyhydroxylated pyrrolidines, belonging to the D-gluco and D-galacto series, through aminocyclization reactions of two differenti