1207745-33-2Relevant academic research and scientific papers
Synthesis and antimicrobial activity of thiazolidinones derived from 4-methylcoumarinyl-7-oxyacetic hydrazide
Manojkumar,Ravi,Gopalakrishnan
experimental part, p. 954 - 958 (2010/08/05)
A series of new thiazolidin-4-ones (3a-j), 5-carboxymethyl-4- thiazolidinones (4a-1) have been synthesised via the condensation of 4-methylcoumarinyl-7-oxyacetic acid [(substituted phenyl)methylene]hydrazides (2a-1), with thioglycolic acid and thiomalic acid respectively. The compounds (2a-1) were synthesised from 4-methylcoumarinyl-7-oxyacetic hydrazide using various aromatic aldehydes. The structure of all synthesised compounds has been determined by spectral methods. The compounds were screened for their antibacterial activity against S. aureus and B. subtilis bacteria.
